About this database:
- Each "worm" lab sends its
most useful strains to the Caenorhabditis
Genetics Center (CGC), but it is not possible to send
every strain. The present database aims at giving access
to the strains collected or generated in the Félix
lab. This collection mostly includes wild isolates
of soil-dwelling nematode isolates (C. elegans,
C. briggsae, Oscheius spp. and a variety
of other species), most of which can be kept frozen, but
some of which we maintain in culture because they do not
recover well after freezing. This lab collection also
includes Oscheius tipulae mutants and genetic tools
generated in C. elegans or O. tipulae for
evolutionary studies, such as introgressed mutant lines
or recombinant inbred lines. In the long term, we plan
to enrich this database with links to further informations
on each strain, especially on the molecular and phenotypic
polymorphism data we are generating in C. elegans
and O. tipulae.
- We try to follow the C.
elegans nomenclature rules. Each strain is designated
by a 2- or 3-letter code, followed by the number of the
strain given by the corresponding lab. The strain code
name for the Félix lab is JU (for JUssieu). For
mutants, each locus is designated by a 3-letter code followed
by a number and each mutant allele by another 1- or 2-letter
lab code followed by a number. The allele code name for
the Félix lab is mf. For example, the JU100
strain is an Oscheius tipulae mutant of genotype
iov-2(mf76). Iov is a CGC/Jonathan Hodgkin-approved
name for mutants in the 'Induction Of the Vulva".
- For Oscheius tipulae
mutants, we use C. elegans phenotypic
categories, such as Dpy (Dumpy) and Unc (Uncoordinated).
However, be aware that the O. tipulae unc-1 gene
is not the homolog of the C. elegans unc-1. Once
the homolog has been determined, the C. elegans
gene name can be used, with Oti- in front of it
to specify the species: for example Oti-lin-39
designates the Oscheius tipulae homolog of C.
elegans lin-39 (and Ppa-lin-39 the Pristionchus
pacificus homolog, Bma-lin-39 the Brugia
malayi homolog, etc.).
- Concerning the zoological nomenclature, be aware
that many nematode species are difficult to identify and
that many are undescribed. If so, the species is designated
by its genus name, followed by sp. (and sometimes a number
if the species has been defined but not named). Because
of fluctuating nomenclature, it is useful to refer to
the strain number (for example see Oscheius tipulae
- For JU strains, the filed
"From" in the database refers to the person(s) in the
lab who generated the strain. For strains that were not generated
by us, the field "From" tries to keep track of the chain
of people (from first to last) through whom the strain arrived
to us. Note that the strain number should not change when the
strain arrives in a new lab.